N,N-二乙基氯甲酰胺合成路线 （共 193 条）
反应条件
2.1: tetramethylethylenediamine; n-BuLi / tetrahydrofuran; hexane / 1 h / -78 °C
2.2: 76 percent / I2 / tetrahydrofuran; hexane / 1 h / -78 °C
View Scheme
参考文献
Lindstroem; Ripa; Hallberg
Organic letters, 2000 , vol. 2, # 15 p. 2291 - 2293
参考文献
Ried; Hillenbrand
Justus Liebigs Annalen der Chemie, 1954 , vol. 590, p. 128,133
参考文献
Ried; Hillenbrand
Justus Liebigs Annalen der Chemie, 1954 , vol. 590, p. 128,133
反应条件
1: 0.08 h / Heating
2: 87 percent Chromat. / tetrahydrofuran / 0.33 h / 20 °C
View Scheme
参考文献
Lemoucheux; Rouden; Lasne
Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9997 - 10001
反应条件
in 1,4-dioxane
T=50 - 60°C;
参考文献
Perveen, Shahnaz; Mustafa, Sana; Khan, Khalid Mohammed
Journal of the Chemical Society of Pakistan, 2010 , vol. 32, # 2 p. 229 - 234
反应条件
in 1,4-dioxane
T=50 - 60°C;
参考文献
Perveen, Shahnaz; Mustafa, Sana; Khan, Khalid Mohammed
Journal of the Chemical Society of Pakistan, 2010 , vol. 32, # 2 p. 229 - 234
反应条件
1: 91.6 percent / KHCO3 / acetone / 48 h / 20 - 30 °C
2: 93.4 percent / AlCl3 / nitrobenzene / 4.5 h / 25 - 30 °C
3: 85 percent KOH / 4 h / 50 - 55 °C
View Scheme
参考文献
Zoelss, G.
Arzneimittel Forschung, 1983 , vol. 33, # 1a p. 2 - 4
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; n-butyllithium in hexane
T=0 - 20°C; 5 h;
参考文献
Panella, Lavinia; Feringa, Ben L.; De Vries, Johannes G.; Minnaard, Adriaan J.
Organic Letters, 2005 , vol. 7, # 19 p. 4177 - 4180
反应条件
in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=0°C;
参考文献
Sengupta, Saumitra; Snieckus, Victor
Journal of Organic Chemistry, 1990 , vol. 55, # 22 p. 5680 - 5683
参考文献
Merck Frosst Canada, Inc.
Patent: US5506227 A1, 1996 ;
US 5506227 A
