N,N-二乙基氯甲酰胺合成路线 （共 193 条）
反应条件
1: 85 percent / sodium hydride / tetrahydrofuran 2: tetrahydrofuran / 0.33 h / -23 °C View Scheme
参考文献
Comins, Daniel L.; Stroud, Eric D.
Tetrahedron Letters, 1986 , vol. 27, # 17 p. 1869 - 1872
反应条件
1: 1.) LDA / 1.) THF, -78 deg C, 60 min, 2.) THF, -78 deg C, 75 min, up to room temp. overnight 2: SmI2 / tetrahydrofuran / 51 h / Ambient temperature View Scheme
参考文献
Zhou, Zhihong; Larouche, Denis; Bennett, Sharon M.
Tetrahedron, 1995 , vol. 51, # 43 p. 11623 - 11644
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide 1) 15-20 deg C; 2) 3 h, room temp.; Yield given;
参考文献
Cerny, Antonin; Benes, Jan; Vachek, Jaroslav; Pesak, Milan; Stuchlik, Josef; et al.
Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 5 p. 1331 - 1339
反应条件
silver nitrate; acetonitrile
参考文献
Norris
Journal of the American Chemical Society, 1959 , vol. 81, p. 3346,3349
反应条件
Produkt5:Distickstoffmonooxid;
参考文献
Norris
Journal of the American Chemical Society, 1959 , vol. 81, p. 3346,3349
反应条件
1: 76 percent / Et3N / CHCl3 / 3 h / Heating 2: 1) AcCl, 2) 4-dimethylaminopyridine / 1) Et2O, 20 min, 2) CH2Cl2, 0 deg C, 2 h View Scheme
参考文献
Akikusa; Mitsui; Sakamoto; Kikugawa
Synthesis, 1992 , # 11 p. 1058 - 1060
反应条件
potassium hydrogencarbonate in acetone T=20 - 30°C; 48 h;
参考文献
Zoelss, G.
Arzneimittel Forschung, 1983 , vol. 33, # 1a p. 2 - 4
反应条件
1: ethanol 2: formic acid View Scheme
参考文献
Kushner et al.
Journal of Organic Chemistry, 1948 , vol. 13, p. 144,149
参考文献
Kushner et al.
Journal of Organic Chemistry, 1948 , vol. 13, p. 144,149
反应条件
1: 3-hydroxy-pyridine With triethylamine in toluene 0.5 h; 2: N,N-diethyl carbamoyl chloride in toluene T=20°C;
参考文献
Miller, Ricarda E.; Rantanen, Toni; Ogilvie, Kevin A.; Groth, Ulrich; Snieckus, Victor
Organic Letters, 2010 , vol. 12, # 10 p. 2198 - 2201
