N,N-二乙基氯甲酰胺合成路线 （共 193 条）
反应条件
triethylamine in tetrahydrofuran T=40°C; 48 h;
参考文献
Joshi, Ramesh A.; Gurjar, Mukund K.; Tripathy, Narendra K.; Chorghade, Mukund S.
Organic Process Research and Development, 2001 , vol. 5, # 2 p. 176 - 178
反应条件
1: 91.6 percent / KHCO3 / acetone / 48 h / 20 - 30 °C 2: 93.4 percent / AlCl3 / nitrobenzene / 4.5 h / 25 - 30 °C 3: 85 percent KOH / 4 h / 50 - 55 °C 4: 48 percent HBr / acetone; H2O / 3 h 5: 71.2 percent / H2O / 25.5 h View Scheme
参考文献
Zoelss, G.
Arzneimittel Forschung, 1983 , vol. 33, # 1a p. 2 - 4
反应条件
lithium diisopropyl amide in tetrahydrofuran T=0 - 20°C;
参考文献
MacNeil, Stephen L.; Wilson, Brian J.; Snieckus, Victor
Organic Letters, 2006 , vol. 8, # 6 p. 1133 - 1136
反应条件
in 1,4-dioxane T=20°C;
参考文献
Perveen, Shahnaz; Fatima, Nasreen; Khan, Muhammad Aitmaud; Dar, Ahsana; Khan, Khalid M.; Afza, Nighat; Voelter, Wolfgang
Medicinal Chemistry Research, 2012 , vol. 21, # 9 p. 2709 - 2715
参考文献
Geigy A.G.
Patent: US2551891 , 1949 ;
参考文献
Ozaki; Nagoya
Bulletin of the Chemical Society of Japan, 1957 , vol. 30, p. 444,448
参考文献
Ozaki; Nagoya
Bulletin of the Chemical Society of Japan, 1957 , vol. 30, p. 444,448
参考文献
Ozaki; Nagoya
Bulletin of the Chemical Society of Japan, 1957 , vol. 30, p. 444,448
反应条件
tributyl-amine T=20°C; 0.333333 h;
参考文献
DIRECTOR GENERAL, DEFENCE RESEARCH and DEVELOPMENT ORGANISATION; RAO, Ambati Narasimha; GANESAN, Kumaran; VIJAYARAGHAVAN, Rajagopalan
Patent: WO2013/65059 A1, 2013 ;
Location in patent: Page/Page column 13; 14 ;
反应条件
bis-triphenylphosphine-palladium(II) chloride; cesium fluoride in tetrahydrofuran T=80°C; 16 h;
参考文献
Lysen, Morten; Kelleher, Susan; Begtrup, Mikael; Kristensen, Jesper Langgaard
Journal of Organic Chemistry, 2005 , vol. 70, # 13 p. 5342 - 5343
