1: With ethyl bromide; magnesium in tetrahydrofuran
T=35 - 50°C; Inert atmosphere;
2: With anhydrous iron chloride; chloroethylmethylchloride in tetrahydrofuran
T=45 - 65°C; Inert atmosphere;
参考文献
Toray Fine Chemicals Co., Ltd.
Patent: EP2100874 A1, 2009 ;
Location in patent: Page/Page column 6-7 ;