5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-2-吡啶甲胺合成路线 （共 3 条）
反应条件
hydrogen; acetic acid; palladium on activated charcoal
T=20°C; 16 h;
参考文献
Wiles, Jason A.; Song, Yongsheng; Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Cheng, Jijun; Marlor, Christopher W.; Ou, Yangsi; Podos, Steven D.; Thanassi, Jane A.; Thoma, Christy L.; Deshpande, Milind; Pucci, Michael J.; Bradbury, Barton J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1277 - 1281
反应条件
1: 100 percent / I2; aq. NH3 / tetrahydrofuran / 4 h / 20 °C
2: 64 percent / PdCl2(dppf); KOAc / dimethylsulfoxide / 25 h / 80 °C
3: 100 percent / H2; acetic acid / Pd/C / 16 h / 20 °C
View Scheme
参考文献
Wiles, Jason A.; Song, Yongsheng; Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Cheng, Jijun; Marlor, Christopher W.; Ou, Yangsi; Podos, Steven D.; Thanassi, Jane A.; Thoma, Christy L.; Deshpande, Milind; Pucci, Michael J.; Bradbury, Barton J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1277 - 1281
反应条件
1: 64 percent / PdCl2(dppf); KOAc / dimethylsulfoxide / 25 h / 80 °C
2: 100 percent / H2; acetic acid / Pd/C / 16 h / 20 °C
View Scheme
参考文献
Wiles, Jason A.; Song, Yongsheng; Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Cheng, Jijun; Marlor, Christopher W.; Ou, Yangsi; Podos, Steven D.; Thanassi, Jane A.; Thoma, Christy L.; Deshpande, Milind; Pucci, Michael J.; Bradbury, Barton J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1277 - 1281
