(6Z)-6-(溴亚甲基)-3-苯基四氢-2H-吡喃-2-酮合成路线 （共 3 条）
反应条件
N-bromosuccinmide; potassium hydrogencarbonate in dichloromethane
参考文献
Washington University
Patent: US5208244 A1, 1993 ;
US 5208244 A
反应条件
N-bromosuccinmide; water; potassium hydrogencarbonate
1.) CH2Cl2, 10 min, 2.) 60 min; Yield given. Multistep reaction;
参考文献
Dai, Wei; Katzenellenbogen, John A.
Journal of Organic Chemistry, 1991 , vol. 56, # 24 p. 6893 - 6896
反应条件
1: lithium diisopropyl amide / tetrahydrofuran / 17 h / -10 - 20 °C
2: N-bromosuccinmide; potassium carbonate / dichloromethane; water / 6 h / 20 °C
View Scheme
参考文献
Mock, Jason N.; Taliaferro, John P.; Lu, Xiao; Patel, Sravan Kumar; Cummings, Brian S.; Long, Timothy E.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4854 - 4858
