sodium hydride in dichloromethane; N,N-dimethyl-formamide Ambient temperature;

1: 78 percent / NaH / dimethylformamide; CH2Cl2 / Ambient temperature 2: 90 percent / water, NaOH / pyridine; methanol / 24 h / Heating View Scheme

1: 78 percent / NaH / dimethylformamide; CH2Cl2 / Ambient temperature 2: 90 percent / water, NaOH / pyridine; methanol / 24 h / Heating 3: 48 percent / BBr3 / CH2Cl2 / 24 h / -35 °C View Scheme