sodium hydride in dichloromethane; N,N-dimethyl-formamide Ambient temperature;

1: H2 / PtO2, 80percent / methanol / 20 h / 25 °C / 735.5 Torr 2: 71 percent / 2,6-lutidine / benzene 3: 62 percent / NaH / dimethylformamide; CH2Cl2 / Ambient temperature View Scheme

1: 43 percent / N,N-dimethylaniline / CH2Cl2 / 2 h / Ambient temperature 2: 60 percent / p-tert-butylcalix<4>arene tetraamide, KOH / CH2Cl2; acetonitrile / 0.5 h View Scheme

sodium hydroxide; water in pyridine; methanol 24 h; Heating;