sodium hydroxide; water in pyridine; methanol 24 h; Heating;

1: 79 percent / 2,6-lutidine / benzene 2: 50 percent / NaH / dimethylformamide; CH2Cl2 / Ambient temperature 3: 60 percent / water, NaOH / pyridine; methanol / 24 h / Heating View Scheme

1: 50 percent / NaH / dimethylformamide; CH2Cl2 / Ambient temperature 2: 60 percent / water, NaOH / pyridine; methanol / 24 h / Heating View Scheme