N,N-二苯甲基-L-丝氨酸甲酯合成路线 (共 7 条)
反应条件
sodium hydrogencarbonate; tetrabutylammomium bromide in water; acetonitrile
参考文献
ASTRAZENECA AB
Patent: WO2008/136746 A1, 2008 ;
Location in patent: Page/Page column 9-10 ;
WO 2008/136746 A1
反应条件
in diethyl ether; ethanol; chloroform T=0°C;
参考文献
Gani, David; Hitchcock, Peter B.; Young, Douglas W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1363 - 1372
反应条件
sodium hydrogencarbonate in tetrahydrofuran; dimethyl sulfoxide Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 14 p. 4315 - 4320
反应条件
(T-4)-trihydro(2-methylpyridine)-boron; acetic acid in methanol T=20°C;
参考文献
Synthesis, , # 10 art. no. F01410SS, p. 1673 - 1677
反应条件
1: 36 percent / 7M-KOH / H2O; ethanol / 1 h / Heating 2: 96 percent / CHCl3; ethanol; diethyl ether / 0 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1363 - 1372
反应条件
PMHS; palladium dihydroxide in ethanol T=20°C; 4 h;
参考文献
Chandrasekhar; Babu, B. Nagendra; Reddy, Ch. Raji
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2057 - 2059
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
参考文献
Ordonez, Mario; Lagunas-Rivera, Selene; Hernandez-Nunez, Emanuel; Labastida-Galvan, Victoria
Molecules, 2010 , vol. 15, # 3 p. 1291 - 1301