1-(4-甲氧基苯基)-1-氧代-2-溴丁烷合成路线 （共 4 条）
反应条件
bromine; acetic acid in diethyl ether
T=20°C;
参考文献
Ghosh, Usha; Ganessunker, Deshanie; Sattigeri, Viswajanani J.; Carlson, Kathryn E.; Mortensen, Deborah J.; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 4 p. 629 - 657
反应条件
aluminium trichloride in 1,2-dichloro-ethane
T=0°C; Friedel-Crafts acylation; 2 h;
参考文献
Wiglenda, Thomas; Gust, Ronald
Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1475 - 1484
反应条件
1: AlCl3, aluminium chloride / dichloromethane / 0 °C
2: bromine / diethyl ether / 1 h / 0 °C
View Scheme
参考文献
Schaefer, Anja; Wellner, Anja; Gust, Ronald
ChemMedChem, 2011 , vol. 6, # 5 p. 794 - 803
反应条件
N,N-dimethyl-aniline
T=170°C;
参考文献
Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447
