N-(4-氯-2-硝基苯基)乙酰胺合成路线 （共 32 条）
参考文献
Justus Liebigs Annalen der Chemie, , vol. 311, p. 113
参考文献
Chemische Berichte, , vol. 33, p. 3062
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 9, p. 101;
Justus Liebigs Annalen der Chemie, , vol. 182, p. 96
参考文献
Chemische Berichte, , vol. 40, p. 374
参考文献
Chemische Berichte, , vol. 39, p. 1262
Justus Liebigs Annalen der Chemie, , vol. 311, p. 113
反应条件
1: hydrogenchloride / water / 2 h / |Reflux 2: potassium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 4 h / 120 °C 3: tin(ll) chloride; hydrogenchloride / 0.25 h / |Reflux 4: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-(N,N-dimethlyamino)pyridine / acetonitrile / |Microwave irradiation View Scheme
参考文献
Yu, Yongguo; Wu, Jianbo; Lei, Fan; Chen, Lei; Wan, Weili; Hai, Li; Guan, Mei; Wu, Yong
Letters in Drug Design and Discovery, 2013 , vol. 10, # 4 p. 369 - 373
反应条件
1.1: hydrogenchloride / water / Reflux 2.1: diethyl ether / 1 h / 100 °C 2.2: 3 h / 50 - 110 °C 2.3: 3 h / 50 - 110 °C 3.1: hydrogenchloride; trifluoroacetic acid; sodium nitrite / water / 1 h / 20 °C 4.1: trichlorophosphate / 3 h / Reflux View Scheme
参考文献
Chopra, Sidharth; Koolpe, Gary A.; Tambo-Ong, Arlyn A.; Matsuyama, Karen N.; Ryan, Kenneth J.; Tran, Tran B.; Doppalapudi, Rupa S.; Riccio, Edward S.; Iyer, Lalitha V.; Green, Carol E.; Wan, Baojie; Franzblau, Scott G.; Madrid, Peter B.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 13 p. 6047 - 6060
反应条件
1: sodium amide; toluene / 140 °C 2: aqueous hydrochloric acid View Scheme
参考文献
King; Acheson
Journal of the Chemical Society, 1946 , p. 681,684
反应条件
(i) NaOAc, P2O5, Ac2O, AcOH, NOHSO4, (ii) /BRN= 969212/; Multistep reaction;
参考文献
Berti,G. et al.
Gazzetta Chimica Italiana, 1977 , vol. 107, p. 175 - 180
参考文献
Wepster; Verkade
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 88,89
反应条件
1: 75 percent / hydrazine hydrate / RaNi 2: aq.HCl / 0.5 h / Heating View Scheme
参考文献
Molchanov, L. V.; Ayupova, A. T.; Kadyrov, Ch. Sh.; Shapkin, V. A.
Chemistry of Natural Compounds, 1983 , vol. 19, # 3 p. 196 - 198
Khimiya Prirodnykh Soedinenii, 1983 , vol. 19, # 3 p. 207 - 209
