N-(4-氯-2-硝基苯基)乙酰胺合成路线 （共 32 条）
反应条件
1: HNO3+H2SO4 / -5 °C 2: concentrated sulfuric acid / 110 °C 3: Diazotization.Behandeln mit Kupfer(I)-chlorid in salzsaurer Loesung 5: iron; acetic acid View Scheme
参考文献
Holleman
Recueil des Travaux Chimiques des Pays-Bas, 1920 , vol. 39, p. 461
反应条件
1: H2SO4 2: H2NNH2.H2O / Raney Ni View Scheme
参考文献
Hall; Turner
Journal of the Chemical Society, 1945 , p. 694,697
反应条件
1: hydrogenchloride / water / 2 h / |Reflux 2: potassium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 4 h / 120 °C 3: tin(ll) chloride; hydrogenchloride / 0.25 h / |Reflux View Scheme
参考文献
Yu, Yongguo; Wu, Jianbo; Lei, Fan; Chen, Lei; Wan, Weili; Hai, Li; Guan, Mei; Wu, Yong
Letters in Drug Design and Discovery, 2013 , vol. 10, # 4 p. 369 - 373
反应条件
sulfuric acid; orthoarsenic acid
参考文献
Magidsson; Bobyschew
Zhurnal Obshchei Khimii, 1938 , vol. 8, p. 909
Chem. Zentralbl., 1939 , vol. 110, # I p. 4953
反应条件
1: H2 / 5percent Pd/C 2: 16.1 percent / dimethylformamide / 167 h / Ambient temperature View Scheme
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
反应条件
1: HNO3+H2SO4 / -5 °C 2: concentrated sulfuric acid / 110 °C 3: Diazotization.Behandeln mit Kupfer(I)-chlorid in salzsaurer Loesung View Scheme
参考文献
Holleman
Recueil des Travaux Chimiques des Pays-Bas, 1920 , vol. 39, p. 461
反应条件
1: conc. sulfuric acid / 0.25 h / 100 °C
2: 1.) aq. HCl, NaNO2, 2.) aq. NaN3, sodium acetate / 1.) 0 deg C, 15 min
3: toluene / 2 h / Heating
View Scheme
参考文献
Monge, Antonio; Palop, Juan A.; Cerain, Adela Lopez de; Senador, Virginia; Martinez-Crespo, Francisko J.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1786 - 1792
反应条件
1: HNO3+H2SO4 / -5 °C
2: concentrated sulfuric acid / 110 °C
3: Diazotization.Behandeln mit Kupfer(I)-chlorid in salzsaurer Loesung
View Scheme
参考文献
Holleman
Recueil des Travaux Chimiques des Pays-Bas, 1920 , vol. 39, p. 461
反应条件
1: 75 percent / hydrazine hydrate / RaNi
2: 60 percent / Heating
View Scheme
参考文献
Molchanov, L. V.; Ayupova, A. T.; Kadyrov, Ch. Sh.; Shapkin, V. A.
Chemistry of Natural Compounds, 1983 , vol. 19, # 3 p. 196 - 198
Khimiya Prirodnykh Soedinenii, 1983 , vol. 19, # 3 p. 207 - 209
反应条件
1: H2 / 5percent Pd/C
2: 29 percent / dimethylformamide / 167 h / Ambient temperature
3: 29.3 percent / Raney Ni / ethyl acetate / 0.83 h / Heating
View Scheme
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
