1: dibenzopyrrole With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=60°C; 0.333333 h; Inert atmosphere;
2: methyl 3-bromo-propionate in N,N-dimethyl-formamide; mineral oil
T=60°C; 4 h; Inert atmosphere;
参考文献
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; KOZIKOWSKI, Alan; BUTLER, Kyle, B.; KALIN, Jay, Hans
Patent: WO2011/11186 A2, 2011 ;
Location in patent: Page/Page column 56-57 ;
WO 2011/011186 A2
1: dibenzopyrrole With sodium hydride in tetrahydrofuran
T=20°C; 2 h;
2: acrylic acid methyl ester in tetrahydrofuran
T=20°C; Michael reaction; 16 h; Further stages.;
参考文献
Williams, David E.; Craig, Kyle S.; Patrick, Brian; McHardy, Lianne M.; Van Soest, Rob; Roberge, Michel; Andersen, Raymond J.
Journal of Organic Chemistry, 2002 , vol. 67, # 1 p. 245 - 258