反应条件
1: 4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-[2-phthalimidoethoxymethyl]-1,4-dihydropyridine With methylamine in water T=20 - 45°C; 4.5 h; 2: benzenesulfonic Acid in water T=20°C; pH=1 - 2; 4.5 h; Product distribution / selectivity;
参考文献
FDC LIMITED; CHANDAVARKAR, Mohan, Anand; SOHANI, Suhas, Vasant; BHOIR, Vijtkumar, Gajanan; SAWANT, Sameer, Narayan
Patent: WO2011/117876 A1, 2011 ;
Location in patent: Page/Page column 11-12 ;