1: 92 percent / (i-Pr)2NH, TMEDA, MeLi / diethyl ether / Ambient temperature 2: 86 percent / 50percent NaH/oil / dimethylformamide / Ambient temperature 3: 98 percent / tert-BuLi / pentane; diethyl ether / 2 h / Ambient temperature 4: 10percent HCl / methanol / 0.17 h / Heating 5: K2CO3 / acetone / 0.75 h / Heating View Scheme

1: 92 percent / (i-Pr)2NH, TMEDA, MeLi / diethyl ether / Ambient temperature 2: 86 percent / 50percent NaH/oil / dimethylformamide / Ambient temperature View Scheme

1: 92 percent / (i-Pr)2NH, TMEDA, MeLi / diethyl ether / Ambient temperature 2: 86 percent / 50percent NaH/oil / dimethylformamide / Ambient temperature 3: 98 percent / tert-BuLi / pentane; diethyl ether / 2 h / Ambient temperature 4: 10percent HCl / methanol / 0.17 h / Heating View Scheme