sodium amide

sodium amide; benzene

in N,N-dimethyl-formamide 24 h; Heating;

1: 72 percent / dimethylformamide / 24 h / Heating 2: 75 percent / p-TsOH / toluene / 6 h / Heating 3: 90 percent / H2 / 10percent palladium-charcoal / aq. ethanol 4: 95 percent / NaOCl / H2O; CH2Cl2 / 3 h / dark 5: 1.) CF3COOH, 2.) potassium carbonate / 1.) MeOH, reflux, 3 h, 2.) reflux, 1 h View Scheme