反应条件
1: 1.) NaOMe, 2.) CuCl / 1.) MeOH,benzene, 2.) pyridine, reflux, 20 h
2: 46 percent / Pd(OAc)2 / trifluoroacetic acid; acetic acid / 2.3 h / Heating
3: 11 percent / 1.) n-BuLi, 2.) lithium salt of t-butylperoxide / 1.) n-hexane, Et2O, 4 deg C, 48 h, 2.) -78 deg C -> RT, then reflux, 5 min
4: diethyl ether
View Scheme
参考文献
Kemp, Malcolm S.; Burden, Raymond S.; Loeffler, R. S. Thomas
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2267 - 2272
