4-羟基-4-(3-甲硫基苯基)-1-丙基哌啶合成路线 (共 3 条)
反应条件
trifluoroacetic acid 0.25 h; Heating / reflux; Product distribution / selectivity;
参考文献
ALLBAY AB
Patent: WO2008/127188 A1, 2008 ;
Location in patent: Page/Page column 19-20; 28 ;
WO 2008/127188 A1
反应条件
1: 1-bromo-3-methylsulphanyl-benzene With magnesium; iodine in diethyl ether
0.833333 h; Heating / reflux;
2: 1-propylpiperidin-4-one in diethyl ether
T=20°C; Product distribution / selectivity;
参考文献
ALLBAY AB
Patent: WO2008/127188 A1, 2008 ;
Location in patent: Page/Page column 18-19 ;
WO 2008/127188 A1
反应条件
Product distribution / selectivity;
参考文献
ALLBAY AB
Patent: WO2008/127188 A1, 2008 ;
Location in patent: Page/Page column 28 ;
WO 2008/127188 A1