3-羟基-2-萘甲酸甲酯合成路线 （共 89 条）
反应条件
1: sodium methylate 2: aqueous alcoholic alkali View Scheme
参考文献
Cohen; Dudley
Journal of the Chemical Society, 1910 , vol. 97, p. 1747
反应条件
man fuegt POCl3 zur erkalteten Schmelze, erhitzt auf 180-200grad, bis die HCl-Entwicklung beendet ist, kocht die zerkleinerte Schmelze mit Wasser aus und krystallisiert aus Pyridin+Wasser;
参考文献
Strohbach
Chemische Berichte, 1901 , vol. 34, p. 4148
反应条件
caesium carbonate 32 h; Heating;
参考文献
Sawyer, J. Scott; Beight, Douglas W.; Smith, Edward C. R.; Snyder, David W.; Chastain, Marcia K.; Tielking, Richard L.; Hartley, Lawrence W.; Carlson, Donald G.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 3 p. 893 - 896
反应条件
potassium carbonate; methyl iodide in DMF (N,N-dimethyl-formamide) T=20°C; 0.25 h;
参考文献
Bayer Corporation
Patent: EP1449834 A2, 2004 ;
Location in patent: Page 16 ;
EP 1449834 A2
参考文献
Lesser; Kranepuhl; Gad
Chemische Berichte, 1925 , vol. 58, p. 2122
反应条件
tert-butylamine in methanol 36 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 59, # 8 p. 2156 - 2163
反应条件
tert-butylamine in methanol 36 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 59, # 8 p. 2156 - 2163
反应条件
tert-butylamine; copper dichloride in methanol
T=23°C; 0.0833333 h; Yields of byproduct given;
参考文献
Hovorka; Scigel; Gunterova; Tichy; Zavada
Tetrahedron, 1992 , vol. 48, # 43 p. 9503 - 9516
反应条件
oxygen; (-)-2,2′-isopropylidenebis[(4S)-4-phenyl-2-oxazoline]; copper(l) chloride in tetrahydrofuran
T=20°C; 3 h;
参考文献
Temma, Tomohisa; Habaue, Shigeki
Tetrahedron Letters, 2005 , vol. 46, # 34 p. 5655 - 5657
反应条件
(+)-1,2,3,4,1',2',3',4'-octahydro-1,1'-bisisoquinoline; copper dichloride in acetonitrile
T=20°C; 27 h;
参考文献
Illesinghe, Jayamini; Ebeling, Richard; Ferguson, Brett; Patel, Jim; Campi, Eva M.; Jackson, W. Roy; Robinson, Andrea J.
Australian Journal of Chemistry, 2004 , vol. 57, # 2 p. 167 - 176
