N-(叔丁基)-2-氟-4-甲基苯磺酰胺合成路线 （共 3 条）
反应条件
in tetrahydrofuran; hexane; toluene
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4479901 A1, 1984 ;
反应条件
in tetrahydrofuran
T=0 - 20°C;
参考文献
GILEAD SCIENCES, INC.; CANALES, Eda; CHONG, Lee, S.; CLARKE, Michael, O'neil Hanrahan; LAZERWITH, Scott, E.; LEW, Willard; LIU, Qi; MITCHELL, Michael, L.; WATKINS, William, J.; ZHANG, Jennifer, R.
Patent: WO2010/2998 A1, 2010 ;
Location in patent: Page/Page column 73 ;
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane
2 h;
2: With N-fluoro-N-(phenylsulfonyl)benzene-sulfonamide in tetrahydrofuran; hexane
3 h; Further stages.;
参考文献
Hashimoto, Hiromasa; Imamura, Katsuaki; Haruta, Jun-Ichi; Wakitani, Korekiyo
Journal of Medicinal Chemistry, 2002 , vol. 45, # 7 p. 1511 - 1517
