T=-78 - 25°C;

1: lithium di-isopropylamide (LDA) / tetrahydrofuran / 1 h / -40 °C 2: 90 percent / -78 - 25 °C View Scheme

1: acetonitrile / 72 h / Ambient temperature 2: lithium di-isopropylamide (LDA) / tetrahydrofuran / 1 h / -40 °C 3: 90 percent / -78 - 25 °C View Scheme