2-甲基喹啉-3,4-二羧酸合成路线 （共 7 条）
反应条件
1: pyridine; acetic anhydride / 3 h / 55 - 60 °C 2: pyridine; NH3; acetic andydride / 0.5 h / Heating View Scheme
参考文献
Kravchenko, Dmitri V.; Kysil, Vladimir V.; Ilyn, Alexey P.; Tkachenko, Sergey E.; Maliarchouk, Sergey; Okun, Ilya M.; Ivachtchenko, Alexandre V.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1841 - 1845
反应条件
potassium hydroxide
24 h; Ambient temperature;
参考文献
Irvine, Robert W.; Summers, John C.; Taylor, Walter C.
Australian Journal of Chemistry, 1983 , vol. 36, # 7 p. 1419 - 1430
反应条件
1: indole-2,3-dione With sodium hydroxide
T=20°C; 1 h;
2: acetoacetic acid methyl ester in water
T=20°C; 12 h;
参考文献
Kravchenko, Dmitri V.; Kysil, Vladimir V.; Ilyn, Alexey P.; Tkachenko, Sergey E.; Maliarchouk, Sergey; Okun, Ilya M.; Ivachtchenko, Alexandre V.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1841 - 1845
参考文献
Pfitzinger
Journal fuer Praktische Chemie (Leipzig), 1897 , vol. <2> 56, p. 292
Full Text Show Details
Engelhard
Journal fuer Praktische Chemie (Leipzig), 1898 , vol. <2> 57, p. 471
参考文献
v. Walther
Journal fuer Praktische Chemie (Leipzig), 1903 , vol. <2> 67, p. 504
反应条件
1: 91 percent / methanol; diethyl ether / 0 °C
2: 3-chloroperbenzoic acid / CHCl3 / 100 h / Ambient temperature
View Scheme
参考文献
Irvine, Robert W.; Summers, John C.; Taylor, Walter C.
Australian Journal of Chemistry, 1983 , vol. 36, # 7 p. 1419 - 1430
反应条件
in methanol; diethyl ether
T=0°C;
参考文献
Irvine, Robert W.; Summers, John C.; Taylor, Walter C.
Australian Journal of Chemistry, 1983 , vol. 36, # 7 p. 1419 - 1430
