反应条件
1: 70 percent / NaH / paraffin; dimethylformamide / 1.) -50 - -40 deg C, 20 min, 2.) -40 to 10 deg C, 30 min
2: 86 percent / phosphoryl chloride / dimethylformamide / 8 h / Ambient temperature
View Scheme
参考文献
Moriya; Seki; Takabe; Matsumoto; Takashima; Mori; Odawara; Takeyama
Journal of Medicinal Chemistry, 1988 , vol. 31, # 6 p. 1197 - 1204
