4-(10-氧代-4,10-二氢噻吩并[3,2-c][1]苯并氧杂卓-8-基)丁酸合成路线 （共 3 条）
反应条件
trifluoroacetic anhydride in dichloromethane
4 h; Heating;
参考文献
Martin, Lawrence L.; Setescak, Linda L.; Spaulding, Theodore C.; Helsley, Grover C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 372 - 376
反应条件
1: K2CO3, KI / butan-2-one / 24 h / Heating
2: aq. KOH / aq. ethanol / 3 h / Heating
3: 73 percent / TFAA / CH2Cl2 / 4 h / Heating
View Scheme
参考文献
Martin, Lawrence L.; Setescak, Linda L.; Spaulding, Theodore C.; Helsley, Grover C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 372 - 376
反应条件
1: aq. KOH / aq. ethanol / 3 h / Heating
2: 73 percent / TFAA / CH2Cl2 / 4 h / Heating
View Scheme
参考文献
Martin, Lawrence L.; Setescak, Linda L.; Spaulding, Theodore C.; Helsley, Grover C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 372 - 376
