3-(苯并[d][1,3]-6-二氧烷)丙肼合成路线 （共 5 条）
反应条件
hydrazine hydrate in ethanol
Substitution; 3 h; Heating;
参考文献
Lima, Patricia C.; Lima, Lidia M.; Da Silva, Kelli Cristine M.; Leda, Paulo Henrique O.; De Miranda, Ana Luisa P.; Fraga, Carlos A. M.; Barreiro, Eliezer J.
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 2 p. 187 - 203
反应条件
hydrazine hydrate in methanol
3 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2810 - 2819
反应条件
1.1: BH3*THF / tetrahydrofuran / 2 h / 20 °C
1.2: 78 percent / 30 percent H2O2; aq. NaOH / tetrahydrofuran; methanol / 4 h / 60 °C
2.1: 92 percent / Jones reagent / acetone / 1 h / 0 °C
3.1: 90 percent / conc. H2SO4 / 2 h / Heating
4.1: 75 percent / 80 percent N2H4*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Lima, Patricia C.; Lima, Lidia M.; Da Silva, Kelli Cristine M.; Leda, Paulo Henrique O.; De Miranda, Ana Luisa P.; Fraga, Carlos A. M.; Barreiro, Eliezer J.
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 2 p. 187 - 203
反应条件
1: 92 percent / Jones reagent / acetone / 1 h / 0 °C
2: 90 percent / conc. H2SO4 / 2 h / Heating
3: 75 percent / 80 percent N2H4*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Lima, Patricia C.; Lima, Lidia M.; Da Silva, Kelli Cristine M.; Leda, Paulo Henrique O.; De Miranda, Ana Luisa P.; Fraga, Carlos A. M.; Barreiro, Eliezer J.
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 2 p. 187 - 203
反应条件
1: 90 percent / conc. H2SO4 / 2 h / Heating
2: 75 percent / 80 percent N2H4*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Lima, Patricia C.; Lima, Lidia M.; Da Silva, Kelli Cristine M.; Leda, Paulo Henrique O.; De Miranda, Ana Luisa P.; Fraga, Carlos A. M.; Barreiro, Eliezer J.
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 2 p. 187 - 203
