N-chloro-succinimide in acetic acid 4.5 h; Ambient temperature;

1.1: 48 percent / HCl / H2O; 2-methyl-propan-2-ol / 0.17 h / 20 °C 2.1: NaH / dimethylformamide 2.2: dimethylformamide View Scheme

1: [2-(5-chloro-1H-indol-3-yl)-ethyl]-carbamic acid methyl ester With sodium hydride in N,N-dimethyl-formamide Metallation; 2: acetyl chloride in N,N-dimethyl-formamide Acetylation;