4-[(苯基硫代)甲基]苯甲酸合成路线 （共 9 条）
反应条件
1: 80 percent / concd H2SO4 / methanol / 24 h / Heating 2: 1.) NaH / 1.) DMF, 0 deg C, 20 min, 2.) DMF, RT, 30 min 3: m-chloroperbenzoic acid / CH2Cl2 / 0.25 h / -78 °C 4: 100 percent / dimethylformamide / 1 h / 110 °C View Scheme
参考文献
DeGraw; Christie; Brown; Kelly; Kisliuk; Gaumont; Sirotnak
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 376 - 380
反应条件
sodium carbonate
3 h;
参考文献
DeGraw; Christie; Brown; Kelly; Kisliuk; Gaumont; Sirotnak
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 376 - 380
反应条件
in ethanol
2 h; Heating;
参考文献
Kassem, Ahmed A.; El-Bardan, Ali A.; Mansour, El-Sayed M. E.
Journal of Chemical & Engineering Data, 1987 , vol. 32, # 4 p. 483 - 485
反应条件
sodium ethanolate in ethanol
T=40°C; also at 50 deg C; Rate constant;
参考文献
Hamed, Ezzat A.; El-Bardan, Ali A.; El-Mallah, Nabila M.
International Journal of Chemical Kinetics, 1996 , vol. 28, # 4 p. 283 - 289
反应条件
sodium ethanolate in ethanol
T=40°C; also at 50 deg C; Rate constant;
参考文献
Hamed, Ezzat A.; El-Bardan, Ali A.; El-Mallah, Nabila M.
International Journal of Chemical Kinetics, 1996 , vol. 28, # 4 p. 283 - 289
反应条件
sulfuric acid; dihydrogen peroxide in acetic acid
24 h; Heating;
参考文献
Kassem, Ahmed A.; El-Bardan, Ali A.; Mansour, El-Sayed M. E.
Journal of Chemical & Engineering Data, 1987 , vol. 32, # 4 p. 483 - 485
反应条件
sulfuric acid in methanol
24 h; Heating;
参考文献
DeGraw; Christie; Brown; Kelly; Kisliuk; Gaumont; Sirotnak
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 376 - 380
反应条件
1: 80 percent / concd H2SO4 / methanol / 24 h / Heating
2: 1.) NaH / 1.) DMF, 0 deg C, 20 min, 2.) DMF, RT, 30 min
View Scheme
参考文献
DeGraw; Christie; Brown; Kelly; Kisliuk; Gaumont; Sirotnak
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 376 - 380
反应条件
1: 80 percent / concd H2SO4 / methanol / 24 h / Heating
2: 82 percent / Oxone / methanol; H2O / 0.5 h / Heating
View Scheme
参考文献
DeGraw; Christie; Brown; Kelly; Kisliuk; Gaumont; Sirotnak
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 376 - 380
