1: With potassium carbonate in acetonitrile
10 h; Heating / reflux;
2: With hydrogenchloride in water; ethyl acetate
3: With ammonia in water
pH=11;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Patent: EP1683790 A1, 2006 ;
Location in patent: Page/Page column 11 ;
EP 1683790 A1