6-甲氧基－苯并噻唑-2-羧酸甲酯合成路线 （共 16 条）
反应条件
1: C27H37ClCuN3; potassium tert-butylate / tetrahydrofuran / 8 h / 80 °C / 760.05 Torr / Inert atmosphere; sealed tube
2: N,N-dimethyl-formamide / 1 h / 80 °C / Inert atmosphere; sealed tube
View Scheme
参考文献
Inomata, Hiroshi; Ogata, Kenichi; Fukuzawa, Shin-Ichi; Hou, Zhaomin
Organic Letters, 2012 , vol. 14, # 15 p. 3986 - 3989
反应条件
in N,N-dimethyl-formamide
T=80°C; 1 h; Inert atmospheresealed tube;
参考文献
Inomata, Hiroshi; Ogata, Kenichi; Fukuzawa, Shin-Ichi; Hou, Zhaomin
Organic Letters, 2012 , vol. 14, # 15 p. 3986 - 3989
反应条件
sodium methylate
2 h; Heating;
参考文献
Amess, Robert; Baggett, Neil; Darby, Paul R.; Goode, Anthony R.; Vickers, Ernest E.
Carbohydrate Research, 1990 , vol. 205, # 1 p. 225 - 233
反应条件
1: 80 percent / aq. NaOH / 0.75 h / Heating
2: 66 percent / tetrahydrofuran; diethyl ether / 2 h / 20 °C
View Scheme
参考文献
Krayushkin; Stoyanovich; Zolotarskaya; Chernoburova; Makhova; Yarovenko; Zavarzin; Martynkin; Uzhinov
Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 2 p. 165 - 176
反应条件
1: NH3 / methanol
2: POCl3
3: Py*HCl / 200 °C
4: (i) Na, liq. NH3, (ii) /BRN= 744134/, aq. MeOH
5: aq. NaOH / Heating
View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
