1: 5 h / 100 °C
2: aq. KOH / ethanol
3: pyridine / 3 h / 0 - 20 °C
4: aq. HCl / ethanol / 1 h / Heating
View Scheme
参考文献
Atwell, Graham, J.; Baguley, Bruce C.; Finlay, Graeme J.; Rewcastle, Gordon W.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1769 - 1776
1: 2 N HCl / ethanol / 1 h / Heating
2: pyridine / 1.) 20 deg C, 1 h, 2.) 100 deg C, 15 min
View Scheme
参考文献
Atwell, Graham J.; Rewcastle, Gordon W.; Denny, William A.; Cain, Bruce F.; Baguley, Bruce C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 367 - 372
hydrogenchloride in ethanol
1 h; Heating; Yield given;
参考文献
Atwell, Graham, J.; Baguley, Bruce C.; Finlay, Graeme J.; Rewcastle, Gordon W.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1769 - 1776
1: pyridine / 3 h / 0 - 20 °C
2: aq. HCl / ethanol / 1 h / Heating
View Scheme
参考文献
Atwell, Graham, J.; Baguley, Bruce C.; Finlay, Graeme J.; Rewcastle, Gordon W.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1769 - 1776
1: aq. KOH / ethanol
2: pyridine / 3 h / 0 - 20 °C
3: aq. HCl / ethanol / 1 h / Heating
View Scheme
参考文献
Atwell, Graham, J.; Baguley, Bruce C.; Finlay, Graeme J.; Rewcastle, Gordon W.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1769 - 1776
Atwell, Graham J.; Rewcastle, Gordon W.; Denny, William A.; Cain, Bruce F.; Baguley, Bruce C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 367 - 372
Atwell, Graham J.; Rewcastle, Gordon W.; Denny, William A.; Cain, Bruce F.; Baguley, Bruce C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 367 - 372