2-n-丙基-4-甲基-6-(1-苯并咪唑-2-基)苯并咪唑合成路线 （共 4 条）
反应条件
1: With PPA; Polyphosphoric acid (PPA)
T=70 - 155°C; 4.75 - 6 h;
2: With sodium hydroxide in water
T=10 - 15°C; pH=5 - 6; 0.25 - 0.5 h;
参考文献
DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.
Patent: WO2006/44754 A2, 2006 ;
Location in patent: Page/Page column 35 ;
反应条件
polyphosphoric acid
T=150 - 155°C;
参考文献
Reddy, Kikkuru Srirami; Srinivasan, Neti; Reddy, Chinta Raveendra; Kolla, Naveenkumar; Anjaneyulu, Yerremilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Organic Process Research and Development, 2007 , vol. 11, # 1 p. 81 - 85
反应条件
1: palladium on activated charcoal; hydrogen / methanol / 4 h / 25 - 35 °C / 2550.26 Torr / |Autoclave
2: sodium hydroxide / water / 5 h / |Reflux
3: polyphosphoric acid / 150 - 155 °C
View Scheme
参考文献
Reddy, Kikkuru Srirami; Srinivasan, Neti; Reddy, Chinta Raveendra; Kolla, Naveenkumar; Anjaneyulu, Yerremilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Organic Process Research and Development, 2007 , vol. 11, # 1 p. 81 - 85
反应条件
1: sodium hydroxide / water / 5 h / |Reflux
2: polyphosphoric acid / 150 - 155 °C
View Scheme
参考文献
Reddy, Kikkuru Srirami; Srinivasan, Neti; Reddy, Chinta Raveendra; Kolla, Naveenkumar; Anjaneyulu, Yerremilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Organic Process Research and Development, 2007 , vol. 11, # 1 p. 81 - 85
