6-(三氟甲基)-3-甲基吲哚合成路线 （共 3 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
5.5 h; Heating / reflux;
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1837329 A1, 2007 ;
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0) in toluene
T=140°C; 5 h;
参考文献
Jensen, Thomas; Pedersen, Henrik; Bang-Andersen, Benny; Madsen, Robert; Jorgensen, Morten
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 888 - 890
反应条件
palladium diacetate; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in ethylene glycol dimethyl ether
T=20 - 80°C; 48 h;
参考文献
Weinrich, Melissa L.; Beck, Hilary P.
Tetrahedron Letters, 2009 , vol. 50, # 50 p. 6968 - 6972
