2,3-二氯吡啶-4-甲醛合成路线 (共 1 条)
反应条件
1: 2,3-dichloropyridine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.333333 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-78°C; 0.25 h; 3: With water in tetrahydrofuran; hexane T=20°C;
参考文献
ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC; ADDEX PHARMA S.A.; CID-NUNEZ, Jose, Maria; OEHLRlCH, Daniel; TRABANCO-SUAREZ, Andres, Avelino; TRESADERN, Gary, John; VEGA RAMIRO, Juan, Antonio; MACDONALD, Gregor, James
Patent: WO2010/130424 A1, 2010 ;
Location in patent: Page/Page column 109-110 ;
WO 2010/130424 A1