1: With sodium hydrogencarbonate in water; acetone T=0°C; 2: With 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; trichloroisocyanuric acid; sodium bromide in water; acetone T=0 - 20°C; 0.333333 h; 3: With hydrogenchloride; sodium carbonate more than 3 stages;

1: With lithium hydroxide; water in 1,4-dioxane T=20°C; 3 h; 2: With hydrogenchloride in water; ethyl acetate

1: potassium carbonate / water; acetone / 0.5 h / 0 - 20 °C 2: palladium on carbon; hydrogen / methanol / 20 °C 3: 2,2,6,6-tetramethyl-piperidine-N-oxyl; 1-methylcyclopentane; trichloroisocyanuric acid; sodium hydrogencarbonate; sodium bromide / acetone View Scheme

1: palladium on carbon; hydrogen / methanol / 20 °C 2: 2,2,6,6-tetramethyl-piperidine-N-oxyl; 1-methylcyclopentane; trichloroisocyanuric acid; sodium hydrogencarbonate; sodium bromide / acetone View Scheme

1: potassium carbonate / water; acetone / 0.5 h / 0 - 20 °C 2: palladium on carbon; hydrogen / methanol / 20 °C 3: 2,2,6,6-tetramethyl-piperidine-N-oxyl; 1-methylcyclopentane; trichloroisocyanuric acid; sodium hydrogencarbonate; sodium bromide / acetone View Scheme

1: With borane-THF in tetrahydrofuran T=0 - 20°C; 0.416667 h; 2: With methanol; acetic acid in tetrahydrofuran