4-氯-6-甲氧基-2-甲基嘧啶-5-胺合成路线 （共 6 条）
参考文献
Wirth, David D; He, Minxia M; Czeskis, Boris A; Zimmerman, Karen M; Roettig, Ulrike; Stenzel, Wolfgang; Steinberg, Mitchell I
European Journal of Medicinal Chemistry, 2002 , vol. 37, # 1 p. 23 - 34
反应条件
sodium methylate 12 h; Ambient temperature;
参考文献
Nemeryuk, M. P.; Sedov, A. L.; Krepelka, I.; Benes, Ya.; Safonova, T. S.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1113 - 1115
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1398 - 1400
反应条件
1: 83 percent / Fe / acetic acid; methanol / 2 h / 60 °C 2: 97 percent / NaOMe / 12 h / Ambient temperature View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , p. 1113 - 1115
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 19, # 10 p. 1398 - 1400
参考文献
Helvetica Chimica Acta, , vol. 41, p. 1806,1812
反应条件
hydrogenchloride; sodium nitrite in water 1.)-5 deg C, 1.5 h 2.)20 deg C, 1.5 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , p. 1113 - 1115
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 19, # 10 p. 1398 - 1400
反应条件
palladium on activated charcoal; ethanol Hydrogenation.unter Zusatz von MgO;
参考文献
Urban; Schnider
Helvetica Chimica Acta, 1958 , vol. 41, p. 1806,1812
