6-溴-1H-吲唑-3-甲酸甲酯合成路线 （共 5 条）
反应条件
sulfuric acid T=90°C; 4 h;
参考文献
F. HOFFMANN-LA ROCHE AG; BURCH, Jason; GOLDSMITH, Richard, A.; ORTWINE, Daniel, Fred; PASTOR, Richard; PEI, Zhonghua
Patent: WO2013/24011 A1, 2013 ;
Location in patent: Page/Page column 51 ;
反应条件
thionyl chloride in methanol T=60°C; 1 h;
参考文献
US2012/214762 A1, ;
Page/Page column 142 ;
参考文献
WO2007/140174 A2, ;
Page/Page column 43 ;
反应条件
potassium carbonate in acetonitrile
T=20°C; 15 h;
参考文献
PHENEX PHARMACEUTICALS AG; KREMOSER, Claus; ABEL, Ulrich; STEENECK, Christoph; KINZEL, Olaf
Patent: WO2011/20615 A1, 2011 ;
Location in patent: Page/Page column 85; 86 ;
参考文献
ELI LILLY AND COMPANY
Patent: WO2007/92751 A2, 2007 ;
Location in patent: Page/Page column 34 ;
