乙基3-氨基-5-苯基-2-噻吩羧酸酯合成路线 （共 9 条）
反应条件
sodium ethanolate in ethanol T=20 - 70°C; 12 h; Inert atmosphere;
参考文献
Murai, Masahito; Hatano, Ryo; Kitabata, Sachie; Ohe, Kouichi
Chemical Communications, 2011 , vol. 47, # 8 p. 2375 - 2377
反应条件
sodium in ethanol T=20 - 25°C; 2 h;
参考文献
Schollberg, K.; Schaefer, H.; Gewald, K.
Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 5 p. 876 - 879
反应条件
sodium ethanolate in ethanol 0.166667 h; Heating;
参考文献
Shishoo, C. J.; Pathak, U. S.; Jain, K. S.; Devani, I. T.; Chhabria, M. T.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 5 p. 436 - 440
反应条件
1.1: gallium(III) bromide / 1,2-dichloro-ethane / 0.08 h / 20 °C / Inert atmosphere 1.2: 12 h / 80 °C / Inert atmosphere 2.1: sodium ethanolate / ethanol / 12 h / 20 - 70 °C / Inert atmosphere View Scheme
参考文献
Chemical Communications, , vol. 47, # 8 p. 2375 - 2377
反应条件
1: 1.) POCl3, 2.) NH2OH*HCl / 1.) 45-55 deg C, room temperature (30 min), 2.) 70-80 deg C, 160 deg C 2: 63 percent / NaOEt / ethanol / 0.17 h / Heating View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 37, # 1 p. 73 - 77
参考文献
Desai, J. R.; Parikh, A. R.; Chauhan, N. A.
Journal of the Indian Chemical Society, 1997 , vol. 74, # 2 p. 160 - 160
参考文献
Shah, Manish; Parikh, Khyati; Parekh, Hansa
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998 , vol. 37, # 1 p. 73 - 77
反应条件
1: 86 percent / 6 h / 160 - 180 °C 2: 70 percent / POCl3, Me2NH / 8 h / Heating View Scheme
参考文献
Shah, Manish; Parikh, Khyati; Parekh, Hansa
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998 , vol. 37, # 1 p. 73 - 77
反应条件
1: With potassium hydroxide in ethanol; water
4 h; Reflux;
2: With phosphoric acid in water
参考文献
Abdillahi, Ismail; Revelant, Germain; Datoussaid, Yazid; Kirsch, Gilbert
Synthesis, 2010 , # 15 art. no. Z07410SS, p. 2543 - 2546
