4-(2-氯-1,1,2-三氟乙氧基)-苯酚合成路线 （共 3 条）
反应条件
1: With sulfuric acid; sodium nitrite in water
T=-2°C;
2: With copper(II) sulfate in water
Heating;
参考文献
Kremlev; Mushta; Moklyarchuk
Russian Journal of Organic Chemistry, 2003 , vol. 39, # 8 p. 1125 - 1129
反应条件
1.1: 57 percent / KOH / acetone / 5 h / 25 °C
2.1: 71 percent / aq. HCl / ethanol / 2 h / Heating
3.1: NaNO2; H2SO4 / H2O / -2 °C
3.2: CuSO4*9H2O / H2O / Heating
View Scheme
参考文献
Kremlev; Mushta; Moklyarchuk
Russian Journal of Organic Chemistry, 2003 , vol. 39, # 8 p. 1125 - 1129
反应条件
1.1: 71 percent / aq. HCl / ethanol / 2 h / Heating
2.1: NaNO2; H2SO4 / H2O / -2 °C
2.2: CuSO4*9H2O / H2O / Heating
View Scheme
参考文献
Kremlev; Mushta; Moklyarchuk
Russian Journal of Organic Chemistry, 2003 , vol. 39, # 8 p. 1125 - 1129
