1H-吲唑-4-硼酸频哪醇酯合成路线 （共 15 条）
反应条件
1.1: potassium acetate / chloroform / 0.17 h / 20 °C / Cooling with ice 1.2: 18 h / Reflux 2.1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 40 h / 80 °C / Inert atmosphere View Scheme
参考文献
WO2012/82997 A1, ;
WO 2012/082997 A1
反应条件
1: hydrogenchloride; water / methanol / 7 h / 20 °C 2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 40 h / 80 °C / |Inert atmosphere View Scheme
反应条件
sodium hydrogencarbonate; bis-triphenylphosphine-palladium(II) chloride in ethanol; water; toluene T=120°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
WO2011/130628 A1, ;
Page/Page column 130 ;
WO 2011/130628 A1
反应条件
sodium carbonate; PdCl2(PPh3)2 in ethanol; water; ethyl acetate; toluene
参考文献
US2010/233164 A1, ;
US 20100233164 A1
反应条件
trifluoroacetic acid in ethyl acetate
参考文献
SPHAERA PHARMA PVT. LTD.; DUGAR, Sundeep; MAHAJAN, Dinesh; HOLLINGER PETER, Frank; SHARMA, Amit; TRIPATHI, Vinayak; KUILA, Bilash
Patent: WO2014/16849 A2, 2014 ;
Location in patent: Page/Page column 113 ;
