3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-羧酸乙酯合成路线 （共 5 条）
反应条件
potassium carbonate in ethanol
T=80°C; 16 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/23235 A1, 2008 ;
Location in patent: Page/Page column 30 ;
参考文献
Brown et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 919,925
参考文献
Ruhemann; Morrell
Journal of the Chemical Society, 1892 , vol. 61, p. 798
Chemische Berichte, 1895 , vol. 28, p. 987
参考文献
Ruhemann; Morrell
Journal of the Chemical Society, 1892 , vol. 61, p. 798
Chemische Berichte, 1895 , vol. 28, p. 987
反应条件
1: With sodium hydroxide; water in methanol
T=70°C; 7 h;
2: With hydrogenchloride in methanol; water
T=0 - 100°C; pH=2; 14 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/23235 A1, 2008 ;
Location in patent: Page/Page column 30 ;
