1-苯基-3-(2-吡啶基)-2-硫脲合成路线 (共 15 条)
反应条件
1: 1-phenyl-3-(pyridin-2-yl)thiourea; phenylchloropyruvic acid methyl ester in dichloromethane 5 h; 2: 1,2-diamino-benzene With acetic acid 1 h; Heating; Further stages.;
参考文献
Mamedov; Zhukova; Beschastnova; Levin; Gubaidullin; Litvinov
Russian Chemical Bulletin, 2007 , vol. 56, # 11 p. 2308 - 2314
反应条件
water; sodium hydroxide in methanol T=80°C;
参考文献
Gallardo-Godoy, Alejandra; Gever, Joel; Fife, Kimberly L.; Silber, B. Michael; Prusiner, Stanley B.; Renslo, Adam R.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 4 p. 1010 - 1021
反应条件
1: NaOAc / acetic acid / Heating
2: aq. HCl / Heating
View Scheme
参考文献
Vladzimirskaya,E.V.
J. Gen. Chem. USSR (Engl. Transl.), 1964 , vol. 34, p. 2774 - 2776,2796 - 2798
反应条件
sodium hydroxide; Neutral lead acetate
参考文献
Feist
Archiv der Pharmazie (Weinheim, Germany), 1934 , vol. 272, p. 100,106
反应条件
sodium acetate in acetic acid
Heating;
参考文献
Gupta; Nath; Shanker; et al.
Journal of the Indian Chemical Society, 1978 , vol. 55, # 8 p. 832 - 834