2,2,2-三氟-1-(6-甲氧基萘-2-基)乙酮合成路线 (共 1 条)
反应条件
1: 2-methoxy-6-bromo-naphthalene With magnesium; ethylene dibromide in diethyl ether
Inert atmosphereReflux;
2: 2,2,2-trifluoro-N-methoxy-N-methylacetamide in diethyl ether
T=0 - 20°C;
3: With hydrogenchloride in diethyl ether; water
参考文献
Yamauchi, Yusuke; Hara, Shoji; Senboku, Hisanori
Tetrahedron, 2010 , vol. 66, # 2 p. 473 - 479