tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=105°C; 1 h;

1: 5-(methoxymethoxy)-2-pyridinecarbonitrile With hydroxylamine in ethanol; water T=0 - 20°C; 1.5 h; 2: acetic anhydride in acetic acid T=20 - 70°C;