7-溴-9h-吡啶并[3,4-b]吲哚合成路线 （共 2 条）
反应条件
bromine in tetrahydrofuran; sodium carbonate
参考文献
Ritzeler, Olaf; Castro, Alfredo; Grenier, Louis; Soucy, Francois; Hancock, Wayne W.; Mazdiyasni, Hormoz; Palombella, Vito; Adams, Julian
Patent: US2002/99068 A1, 2002 ;
反应条件
1: 96 percent / trifluoroacetic acid / 0.5 h
2: 73 percent / NaBH4, BF3*OEt2 / tetrahydrofuran / 2 h / Heating
3: 1.) KOH, 2.) HCl / 1.) water, 1 h, 2.) water, heating
4: 15 percent / S8 / xylene / 4 h / 128 °C
View Scheme
参考文献
Schumacher, Robert W.; Davidson, Bradley S.
Tetrahedron, 1999 , vol. 55, # 4 p. 935 - 942
