6-溴-1-(3,4-二氢-2H-吡咯-5-基)-9H-beta-咔啉合成路线 （共 13 条）
反应条件
1: SOCl2
2: 74 percent / NaOH / H2O; CH2Cl2 / 1 h
3: 74 percent / PPE / CH2Cl2 / 0.83 h / Heating
4: 90 percent / DDQ / benzene / Ambient temperature
5: 80 percent / NBS / CH2Cl2 / 0.75 h / Ambient temperature
View Scheme
参考文献
Hino, Tohru; Lai, Ziping; Seki, Hiroko; Hara, Ritsuko; Kuramochi, Tadao; Nakagawa, Masako
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2596 - 2600
反应条件
1: 90 percent / DDQ / benzene / Ambient temperature
2: 80 percent / NBS / CH2Cl2 / 0.75 h / Ambient temperature
View Scheme
参考文献
Hino, Tohru; Lai, Ziping; Seki, Hiroko; Hara, Ritsuko; Kuramochi, Tadao; Nakagawa, Masako
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2596 - 2600
反应条件
1: 48 percent / trimethylsilyl iodide / CHCl3 / 0.25 h / Ambient temperature
2: 90 percent / DDQ / benzene / Ambient temperature
3: 80 percent / NBS / CH2Cl2 / 0.75 h / Ambient temperature
View Scheme
参考文献
Hino, Tohru; Lai, Ziping; Seki, Hiroko; Hara, Ritsuko; Kuramochi, Tadao; Nakagawa, Masako
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2596 - 2600
