3,3-二甲基-1-(三氟甲基)-1,2-苯并碘氧杂戊环合成路线 （共 71 条）
反应条件
fluoride in acetonitrile
参考文献
Kieltsch, Iris; Eisenberger, Patrick; Stanek, Kyrill; Togni, Antonio
Chimia, 2008 , vol. 62, # 4 p. 260 - 263
反应条件
cesium fluoride in acetonitrile T=23°C; 16 h; Inert atmosphereDarkness;
参考文献
Powers, David C.; Lee, Eunsung; Ariafard, Alireza; Sanford, Melanie S.; Yates, Brian F.; Canty, Allan J.; Ritter, Tobias
Journal of the American Chemical Society, 2012 , vol. 134, # 29 p. 12002 - 12009
反应条件
(trifluoromethyl)-trimethylsilane in acetonitrile T=-10°C; 1 h; Inert atmosphere;
参考文献
Matousek, Vaclav; Pietrasiak, Ewa; Schwenk, Rino; Togni, Antonio
Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6763 - 6768
反应条件
1.1: diethyl ether / 3 h / 0 - 23 °C / Inert atmosphere 1.2: 1 h / 23 °C / Inert atmosphere 2.1: acetonitrile / 16 h / 23 °C / Inert atmosphere; Darkness 3.1: cesium fluoride / acetonitrile / 16 h / 23 °C / Inert atmosphere; Darkness View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 29 p. 12002 - 12009
反应条件
1: 100 percent / acetonitrile / 15 h / 20 °C 2: 46 percent / CsF / acetonitrile / 16 h / 20 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 12, # 9 p. 2579 - 2586
反应条件
1: tBuOCl 2: 100 percent / acetonitrile / 15 h / 20 °C 3: 46 percent / CsF / acetonitrile / 16 h / 20 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 12, # 9 p. 2579 - 2586
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 14 h / 23 °C 2.1: diethyl ether / 3 h / 0 - 23 °C / Inert atmosphere 2.2: 1 h / 23 °C / Inert atmosphere 3.1: acetonitrile / 16 h / 23 °C / Inert atmosphere; Darkness 4.1: cesium fluoride / acetonitrile / 16 h / 23 °C / Inert atmosphere; Darkness View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 29 p. 12002 - 12009
反应条件
1.1: sulfuric acid; sodium nitrite / water / 0 - 7 °C / |Inert atmosphere 1.2: 1.58 h / -5 - 80 °C / |Inert atmosphere 2.1: diethyl ether / -30 °C / |Inert atmosphere 3.1: trichloroisocyanuric acid / acetonitrile / 0.17 h / 75 °C / |Inert atmosphere; |Reflux 4.1: potassium fluoride / acetonitrile / 12 h / 20 °C / |Inert atmosphere 5.1: (trifluoromethyl)-trimethylsilane / acetonitrile / 1 h / -10 °C / |Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 78, # 13 p. 6763 - 6768
参考文献
Kieltsch, Iris; Eisenberger, Patrick; Togni, Antonio
Angewandte Chemie - International Edition, 2007 , vol. 46, # 5 p. 754 - 757
反应条件
copper(l) iodide; 1,10-phenanthroline; potassium carbonate in diethylene glycol dimethyl ether T=35°C; 14 h; Inert atmosphere;
参考文献
Liu, Tianfei; Shen, Qilong
Organic Letters, 2011 , vol. 13, # 9 p. 2342 - 2345
