3,6-二氟-2-甲氧基苯甲醛合成路线 (共 1 条)
反应条件
1: 2,5-difluoroanisole With sec.-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-70 - 20°C; 1 h; 3: With hydrogenchloride in tetrahydrofuran; hexane; water
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2007/30582 A2, 2007 ;
Location in patent: Page/Page column 86 ;
WO 2007/030582 A2