sodium hydride in tetrahydrofuran 0.166667 h; Ambient temperature;

1: CHCl3 / 0.5 h / Ambient temperature 2: LDA / tetrahydrofuran / Ambient temperature; 1.) -78 deg C, 2.) RT, 10 h 3: 1.) RhCl3*3H2O, 2.) conc. HCl / 1.) ethanol, reflux, 14 h, 2.) reflux, 20 min 4: 92 percent / NaH / tetrahydrofuran / 0.17 h / Ambient temperature View Scheme

1: 1.) RhCl3*3H2O, 2.) conc. HCl / 1.) ethanol, reflux, 14 h, 2.) reflux, 20 min 2: 92 percent / NaH / tetrahydrofuran / 0.17 h / Ambient temperature View Scheme

1: LDA / tetrahydrofuran / Ambient temperature; 1.) -78 deg C, 2.) RT, 10 h 2: 1.) RhCl3*3H2O, 2.) conc. HCl / 1.) ethanol, reflux, 14 h, 2.) reflux, 20 min 3: 92 percent / NaH / tetrahydrofuran / 0.17 h / Ambient temperature View Scheme