5-溴-2,3-二氟苄基乙醇合成路线 （共 2 条）
反应条件
sodium tetrahydroborate; ammonium carbonate in ethanol
0.5 h;
参考文献
Jarchow-Choy, Sarah K.; Sjuvarsson, Elena; Sintim, Herman O.; Eriksson, Staffan; Kool, Eric T.
Journal of the American Chemical Society, 2009 , vol. 131, p. 5488 - 5494
反应条件
1: N-bromosuccinmide; sulfuric acid / 4 h / 60 °C / |Inert atmosphere
2: sodium tetrahydroborate / methanol / 2.5 h / 0 - 20 °C
View Scheme
参考文献
NOVIRA THERAPEUTICS, INC.; HARTMAN, George D.; FLORES, Osvaldo A.
Patent: WO2013/96744 A1, 2013 ;
